Head, QSP Modeling
Description
Cornerstone Search Group has been retained by a profitable and stable European pharmaceutical company which prides itself on a work environment that reflects its country’s renowned culture, has a mutli-billion dollar market cap, is Oncology and Neurology focused, and has its US HQ in the New York Metropolitan Area. This hybrid role is a newly created, cross-functional, and wide-ranging Quantitative Systems Pharmacology strategic leadership position. As QSP domain owner, you will lead the efforts of building this new, dedicated capability. You will report to a dynamic, and digitally oriented R&D leader who reports to the Global Head of R&D and whom leads an agile and entrepreneurial department that develops and deploys advanced analytics and innovative methodologies with the aim of unearthing new insights and streamline research processes in order to reshape healthcare outcomes. With a product portfolio featuring a recent blockbuster and the upcoming launch of another anticipated blockbuster, this company is in a very active phase of building out their clinical pipeline through both in-house research and in-licensing efforts. Our client is seeking an entrepreneurial professional who will be excited to build a dedicated QSP capability as part of this company’s committment to a more digital and data-driven R&D approach.
WORK AUTHORIZATION: Our client will consider candidates who require an H-1B transfer, TN-Visa, or equivalent, as well as Green Card / Permanent Resident sponsorship.
COMPENSATION: Highly competitive compensation.
Location
LOCATION: Hybrid
Our client will consider candidates who live in the New York Metropolitan Area (NJ, CT, NY State) as well as in the Northeast/Atlantic states (PA, MA, MD, DC, DE, RI) who prefer/require a hybrid work arrangement where they only work on-site on a limited basis.
Features
4 ATTRACTIVE FEATURES:
- "Best of Both Worlds" Environment: This is aniquely attractive opportunity to lead the efforts of building a dedicated QSP function for a well-financed, public company with a multi-billion-dollar market cap but that has a small company feel with very few layers.
- Big Impact: As you will be building and leading their QSP efforts, you will have an outsized impact on this company's future. You will work closely with the senior leaders in R&D (Discovery through to Pre-clinical and Clinical Development) on integrating QSP modeling into all facets of R&D. You will be counted on to develop strategies and processes for a role that will have great strategic impact on the company, which is undergoing an exciting metamorphosis by becoming a more digital, data-driven R&D enterprise.
- Our client’s lead marketed drug is an oncology blockbuster, and their lead clinical candidate is in Phase III and is anticipated to also become an oncology blockbuster. Our client has a long-term focus in Oncology and CNS / Neurology and has a proven history of discovering and developing multiple drugs that have been marketed in the US by multiple Big Pharmas. Our client is now focused on taking the next step in their growth to become a globally integrated pharma.
- This company takes a lot of pride in its culture, reflecting its country’s heritage as having one of the world’s most positive populace.
Responsibilities
RESPONSIBILITIES in a NUTSHELL:
- Build QSP models integrating biological, pharmacological, and physiological data to support drug development at all stages, from preclinical research to clinical trials and beyond, aiding in dose optimization, biomarker identification, safety and efficacy assessment, drug development decision-making, etc.
- Collaborate with internal and external experts, teams, and projects, helping to develop innovative methods for modeling efficacy and safety.
- While part of their computational biology team, you will create your own methods and pipelines, prominently contributing to their shift towards more data-driven research and development.
- Extensive collaboration with internal/external functions, partners, and research biologists is expected.
Qualifications / Requirements
DESIRED SKILLS / QUALIFICATIONS / EXPERIENCES / BEHAVIORS:
- PhD in a relevant field (e.g., biology, math, pharmacology, biomedical engineering, chemical engineering, computation biology, computer science, etc.)
- Senior / Principal / AD / Director-level QSP experience either with a pharma/biotech or for a consulting company or academic research department that services pharma/biotech.
- Extensive experience with exploratory data analysis, modeling and simulation with programming languages such as Python and R is required.
- Our client is open on therapeutic areas of experience/expertise. Oncology, Neurology, and/or Immunology experiences are a plus.
- Seeking someone who values being part of and contributing to a company that is very culture focused. Seeking excellent team working skills and the communication ability to positively encourage and energize others to reach high performance. Seeking someone who is transparent, flexible, builds trusting relationships, and is highly collaborative.
- Seeking a proactive, self-motivated, and entrepreneurial individual who has the ability to prioritize and get things done.
- Seeking a biotech mindset - someone who is innovative and gets excited when looking into new ideas and acquiring scientific knowledge.
Contact
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Keywords
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